Paul A. Randazzo
Senior Investigator
Center for Cancer Research
National Cancer Institute
United States of America
Biography
Paul Randazzo received his M.D. and Ph.D. from Brown University. He received residency training in anatomic pathology at the Hospital of the University of Pennsylvania, predoctoral training in the laboratory of John N. Fain and postdoctoral training in the laboratory of Richard A. Kahn.
Research Interest
1) Ras-superfamily Guanine Nucleotide Binding Proteins 2) ADP-ribosylation factor Guanine Nucleotide Binding Proteins (Arfs) 3) GTPase-activating proteins (GAPs) 4) Guanine nucleotide exchange factors (GEFs)
Publications
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Shiba Y, Randazzo PA. ArfGAP1 function in COPI mediated membrane traffic: currently debated models and comparison to other coat-binding ArfGAPs. Histology and histopathology. 2012 Sep;27(9):1143-53.
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Chen PW, Jian X, Luo R, Randazzo PA. Approaches to studying Arf GAPs in cells: in vitro assay with isolated focal adhesions. Current protocols in cell biology. 2012 Jun 20:17-3.
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Shiba Y, Kametaka S, Waguri S, Presley JF, Randazzo PA. ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment. Current Biology. 2013 Oct 7;23(19):1945-51.
