Prabhakar R. Gudla

Biography

Dr. Gudla received his B. Tech degree in Chemical Engineering from the National Institute of Technology, Trichy, India in 1998. He completed his doctoral research at the Bioengineering Department, University of Maryland at College Park in 2005, where he worked on integrating multiscale mathematical models for understanding biological systems. In 2005, Dr. Gudla joined the Optical Imaging and Analysis Laboratory (Leidos Biomedical Research, Inc., NCI-Frederick) as a Research Scientist. Here, under the supervison of Dr. Stephen J. Lockett, he developed quantitative bioimaging tools for understanding tumorigenesis in live cells and tissues. Then in 2013, he worked with the RAS Imaging Group (NCI RAS Initiative) at the Frederick National Laboratory. Here, he used single molecule imaging techniques to understand KRAS4b dynamics at plasma membrane in live cells and also developed custom quantitative imaging workflows RAS Screening Assay. In 2016, Dr.Gudla was appointed as a Staff Scientist in the High-Throughput Imaging Facility (HiTIF), LRBGE, CCR.

Research Interest

1) Bioimage informatics, 2) single molecule and localization microscopy, 3) machine learning, 4) fluorescence fluctuation spectroscopy, 5) high content imaging, 6) Biomedical Engineering and Biophysics, 7) Cancer Biology.