Siddhartha A.k. Datta
Scientist
Retroviral Replication Laboratory, HIV Dynamics and Replicat
National Cancer Institute
United States of America
Biography
Dr. Siddhartha Datta completed his M.Sc. in biochemistry from Maharaja Sayajirao University, Vadodara, India and earned his Ph.D in biochemistry and biophysics while at the Center for Cellular and Molecular Biology, Hyderabad, India. His studies towards a Ph.D involved investigating the mechanistic properties of the alpha-crystallins, small heat shock proteins involved in maintenance of eye lens transparency. Dr. Datta pursued his postdoctoral training in the lab of Dr. Alan Rein in the Retroviral Assembly Section, HIV Drug Resistance Program, NCI, where he is currently a staff scientist.
Research Interest
1) Protein biochemistry, 2) virology/HIV, 3) optical spectroscopy, 4) mass spectroscopy, 5) analytical centrifugation, 6) combination of biophysical, biochemical, and molecular biology techniques to dissect the mechanisms involved in retroviral assembly, with special emphasis on HIV
Publications
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On the role of the SP1 domain in HIV-1 particle assembly: a molecular switch?
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Diverse interactions of retroviral Gag proteins with RNAs.
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Solution properties of murine leukemia virus gag protein: differences from HIV-1 gag.
