Molecular Biology
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Stephanie L. Goff

Staff Clinician
Center for Cancer Research
National Cancer Institute
United States of America

Stephanie L. Goff

Biography

"Stephanie Goff is a surgeon on the senior staff of the Surgery Branch of the National Cancer Institute at the NIH. Her research interests include adoptive cell therapy for the treatment of solid tumors, building on the backbone of success in patients with metastatic melanoma to investigate the strategy in patients with metastastic breast cancer. Her publications range from analysis of early trials of checkpoint blockade to genetic modifications of T-cell receptors. She is an honors graduate of the Georgia Institute of Technology (Mechanical Engineering) and obtained her MD at the University of South Florida in Tampa. After training in tumor immunology under Dr. Steven Rosenberg, Dr. Goff completed her general surgery residency at Columbia University followed by a surgical oncology fellowship at the combined Dana-Farber Cancer Institute/Brigham and Women’s Hospital/Massachusetts General Hospital program."

Research Interest

immunotherapy, melanoma, breast cancer, surgical oncology

Publications

  • Feldman SA, Assadipour Y, Kriley I, Goff SL, Rosenberg SA. Adoptive cell therapy—tumor-infiltrating lymphocytes, T-cell receptors, and chimeric antigen receptors. InSeminars in oncology 2015 Aug 1 (Vol. 42, No. 4, pp. 626-639). Elsevier.

  • Assadipour Y, Zacharakis N, Crystal JS, Prickett TD, Gartner JJ, Somerville RP, Xu H, Black MA, Jia L, Chinnasamy H, Kriley I. Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer. Clinical Cancer Research. 2017 Aug 1;23(15):4347-53.

  • Goff SL, Dudley ME, Citrin DE, Somerville RP, Wunderlich JR, Danforth DN, Zlott DA, Yang JC, Sherry RM, Kammula US, Klebanoff CA. Randomized, prospective evaluation comparing intensity of lymphodepletion before adoptive transfer of tumor-infiltrating lymphocytes for patients with metastatic melanoma. Journal of Clinical Oncology. 2016 May 23;34(20):2389-97.

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