Tatiana S. Karpova
Facility Head
Center for Cancer Research
National Cancer Institute
United States of America
Biography
Tatiana Karpova obtained her Ph.D. in genetics from St. Petersburg State University (Leningrad, Russia) in 1984. From 1984-1991 she worked as an instructor and then as a senior lecturer in the Department of Genetics at St. Petersburg State University and conducted research in the field of genetic control of translation and translation termination factors in yeast. In 1991 Dr. Karpova was awarded the FEBS fellowship for research at Vrije University (Amsterdam, Holland). From 1992-1999 Dr. Karpova was a postdoctoral fellow in the Department of Cell Biology and Physiology, Washington University School of Medicine (St. Louis, MO). Her research involved genetics and microscopy of actin cytoskeleton in yeast. Dr. Karpova was one of the first scientists able to observe the actin cytoskeleton using green fluorescent protein (GFP) fusion protein markers in live yeast. In 1993-1995 she was awarded an American Heart Association Fellowship. From 1999 to date, Dr. Karpova has managed the NCI Core Fluorescence Imaging Facility.
Research Interest
Fluorescence Imaging
Publications
-
Karpova TS, Baumann CT, He L, Wu X, Grammer A, Lipsky P, Hager GL, McNally JG. Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser. Journal of microscopy. 2003 Jan 1;209(1):56-70.
-
Karpova TS, Chen TY, Sprague BL, McNally JG. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeller. EMBO reports. 2004 Nov 1;5(11):1064-70.
-
Karpova TS, Kim MJ, Spriet C, Nalley K, Stasevich TJ, Kherrouche Z, Heliot L, McNally JG. Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science. 2008 Jan 25;319(5862):466-9.
