Oncology
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Teresa S Hawley

Research Biologist
Laboratory of Genome Integrity, CCR
National Cancer Institute
United States of America

Biography

Teresa Hawley received her B.S. (summa cum laude) in Biology from the University of Wisconsin-Eau Claire in 1973. Before entering the flow cytometry field, she worked as a biomedical researcher at the Ontario Cancer Institute in Toronto from 1974 to 1984, and at the Fox Chase Cancer Center in Philadelphia from 1984 to 1987. Areas of research included molecular and cell biology, immunology, hematology, oncology, and virology. From 1987 to 1999, she participated in cancer research at the Ottawa Cancer Center, University of Toronto’s Sunnybrook Health Science Center, and the Toronto General Hospital. From 1999 to 2004, Teresa was a Project Leader at the Jerome H. Holland Laboratory for the Biomedical Sciences – the national research and development division of American Red Cross Biomedical Services – in Rockville, MD, responsible for establishing and overseeing the institute’s Flow Cytometry Facility. She assumed the role of Director of the Flow Cytometry Core Facility at the George Washington University in July 2004. In October 2015, she joined the NCI Laboratory of Genome Integrity Flow Cytometry Core Facility at the NIH. Teresa has published over 85 original and review articles in peer-reviewed scientific journals and books. In addition, she co-edited the second and third editions of Flow Cytometry Protocols in the Methods in Molecular Biology series published by Humana Press/Springer. The fourth edition is currently in preparation. She has given lectures to undergraduate and graduate students, and has been a faculty member at the Annual National Courses in Flow Cytometry since 2004.

Research Interest

1) Polychromatic analysis and sorting, 2) conventional and spectral analysis of fluorescent proteins, 3) drug resistance mechanisms in multiple myeloma, 4) hematopoietic stem cell biology, 5) side population analysis

Publications

  • Interferon-γ links ultraviolet radiation to melanomagenesis in mice.

  • Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1.

  • Multiparametric flow cytometry using near-infrared fluorescent proteins engineered from bacterial phytochromes.

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