Graeme J Wistow
Senior Investigator
Section on Molecular Structure and Functional Genomics
National Eye Institute
United States of America
Biography
Dr. Wistow received his BA in Biochemistry from Oxford University, UK in 1976 and his Ph.D. in Protein X-ray crystallography from the University of London, UK in 1982. His thesis work described the first three-dimensional structure of a γ-crystallin. He joined NEI in 1982 and became a Section Chief in 1989. Dr. Wistow received NEI Director’s Awards in 1991 and 2000, an NEI Appreciation award in 2005 and an NIH Director’s Award in 2001. In 1997 he received the Cogan Award of the Association for Research in Vision and Ophthalmology "In recognition of outstanding and promising research on the structure and function of the lens".
Research Interest
Vision and Ophthalmology
Publications
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Fan J, Jia L, Li Y, Ebrahim S, May-Simera H, Wood A, Morell RJ, Liu P, Lei J, Kachar B, Belluscio L. Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse. Proceedings of the National Academy of Sciences. 2017 May 23;114(21):E4271-80.
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Mishra S, Peterson K, Yin L, Berger A, Fan J, Wistow G. Accumulation of cholesterol and increased demand for zinc in serum-deprived RPE cells. Molecular vision. 2016;22:1387.
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Sagar V, Chaturvedi SK, Schuck P, Wistow G. Crystal Structure of Chicken γS-Crystallin Reveals Lattice Contacts with Implications for Function in the Lens and the Evolution of the βγ-Crystallins. Structure. 2017 Jul 5;25(7):1068-78.
