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Ophthalmology Experts

Tiansen Li

Senior Investigator
Retinal Cell Biology and Degeneration Section
National Eye Institute
United States of America

Biography

Tiansen Li, Ph.D. is a senior investigator at the Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute. He received his Ph.D. from Purdue University and did post-doctoral training in the Visual Sciences Center, University of Chicago. Prior to joining NEI, he was a principal investigator at the Department of Ophthalmology, Harvard Medical School at the Massachusetts Eye and Ear Infirmary. His primary research interest is in the inherited forms of retinal degeneration including its disease mechanism and therapies.

Research Interest

Ophthalmology and Cell Biology

Publications

  • Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma

  • Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss

  • Sun X, Pawlyk B, Xu X, Liu X, Bulgakov O, Adamian M, Sandberg MA, Khani SC, Tan MH, Smith AJ, Ali RR. Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations. Gene therapy. 2010 Jan;17(1):117.

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