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Biochemistry Experts

Brian Kloss

Professor
Structural Biology
New York Structural Biology
United States of America

Biography

Brian Kloss began his research career as a graduate student in the Laboratory of Carter Bancroft at the Mount Sinai School of Medicine, studying the transcriptional regulation of the pituitary-specific prolactin and growth hormone genes. He went on to do a Postdoc with Michael Young at Rockefeller University, studying the genetic control of circadian rhythms in Drosophila melanogaster. Afterwards, he spent almost six years at a biotech startup, helping to develop a cell-based assay for the screening of ligands of GPCRs. For the past ten years, he has been a part of the protein production facility of the Center on Membrane Protein Production and Analysis (COMPPÅ), located at the New York Structural Biology Center. There, he has led a small group focused on the identification, cloning and expression screening of integral membrane proteins of prokaryotic origin, mainly for structural studies. Brian Kloss began his research career as a graduate student in the Laboratory of Carter Bancroft at the Mount Sinai School of Medicine, studying the transcriptional regulation of the pituitary-specific prolactin and growth hormone genes. He went on to do a Postdoc with Michael Young at Rockefeller University, studying the genetic control of circadian rhythms in Drosophila melanogaster. Afterwards, he spent almost six years at a biotech startup, helping to develop a cell-based assay for the screening of ligands of GPCRs. For the past ten years, he has been a part of the protein production facility of the Center on Membrane Protein Production and Analysis (COMPPÅ), located at the New York Structural Biology Center. There, he has led a small group focused on the identification, cloning and expression screening of integral membrane proteins of prokaryotic origin, mainly for structural studies.

Research Interest

Biochemistry

Publications

  • Structural genomics of integral membrane proteins - Past successes and future directions

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