Robert J. Boylan
Associate Professor
Basic Science and Craniofacial Biology
New York University
United States of America
Biography
1963 B.S. University of Scranton 1967 M.S. Duquesne University 1970 Ph.D. University of Maryland 1970-73 Postdoc University of Rochester School of Medicine and Dentistry
Research Interest
* Gram-negative bacteria involved in periodontal disease. * Bacterial surface proteins involved in adhesion. * Mixed bacterial infections. Our laboratory is developing methods to rapidly identify bacteria in dental plaque that contribute to periodontal disease. We are using DNA probes that specifically identify species, and even subspecies, of the anaerobic, gram-negative rods implicated in this disease without growing the bacteria. We also look at the virulence factors produced by these bacteria and how the bacteria work together to cause more serious episodes of the disease. We have recently begun to look for bacteriophage-encoded lysins of oral bacteria with the expectation that these lysins could be used therapeutically to treat infections of the oral cavity.
Publications
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Craig, RG, Yip, J, So, MK, Boylan, RJ, Haffajee, AD, Socransky, SS. (2003) Relationship of Destructive Periodontal Disease to the Acute-Phase Response. Periodontol 74:1007-1016.
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Craig, R G., R Boylan, J Yip, et al 2002 Serum IgG antibody response to periodontal pathogens in minority populations: Relationship to periodontal disease status and progression. J. Periodont Res. 37 :132-146.
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Craig, RG, Boylan, RJ, J Yip, P. Bamgboye, P. Koutsoukos, D. Mijares, J Ferrer, M. Imam, S. S. Socransky and A.D. Haffajee, 2001 Prevalence and risk indicators for destructive periodontal diseases in 3 urban American minority populations. J. Clin. Periodontal.28:524-535.
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Russell, SL, Boylan, RJ, Kaslick, S, Scannapieco, FA and Katz, RV. (1999) Respiratory pathogen colonization of the dental plaque of institutionalized elders. SCD Special Care in Dentistry. 19:128-134.
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Adamo, HL, Buruiana, R, Schertzer, L and Boylan RJ. (1999) A comparison of Mf~ Super-EB~ composite and amalgam as root-end filling materials using a bacterial microleakage model. International Endodontic Journal. 32:197-203.
