Clinical Research

Clinical Research Experts

Anthony Blikslager

North Carolina State University
United States of America


Dr. Blikslager received his DVM from the Virginia-Maryland Regional College of Veterinary Medicine in 1989, and his PhD in Gastrointestinal Physiology from NC State University in 1997. He is a former head of the Department of Clinical Sciences at the NC State College of Veterinary Medicine. Dr. Blikslager has received numerous honors including the Applied Equine Research Award from the World Equestrian Veterinary Association, the Pfizer Award for Excellence in Research from the NC State College of Veterinary Medicine, and was inducted as a Fellow of the American Gastroenterological Association.

Research Interest

Gastrointestinal Physiology, studying mechanisms responsible for maintenance and restoration of the intestinal barrier, with the ultimate objective of pharmacologically restoring the mucosal barrier in patients suffering from diseases associated with increased intestinal permeability. Restoring the intestinal barrier would be of particular significance in patients suffering from diseases such as intestinal ischemia/reperfusion injury, inflammatory bowel diseases, and gastric ulcer disease because of the potential medical complications associated with these diseases.


  • Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors.Cuppoletti J, Blikslager AT, Chakrabarti J, Nighot PK, Malinowska DH. | BMC Pharmacol 2012;12:1-12

  • Dietary long-chain PUFA enhance acute repair of ischemia-injured intestine of suckling pigs.Jacobi SK, Moeser AJ, Corl BA, Harrell RJ, Blikslager AT, Odle J | J Nutr 2012;142:1266-71

  • Gastro protective properties of the novel prostone SPI-8811 against acid-injured porcine mucosa.Nighot M, Moeser A, Ueno R, Blikslager AT. | World J Gastroenterol 2012;18:4684-92.

  • Return to use and performance following exploratory celiotomy for colic in horses: 195 cases (2003-2010).Davis W, Fogle CA, Gerard MP, Levine JF, Blikslager AT. | Equine Vet J 2013:45:224-28. Featured at the AAEP Kester News Hour, 2013

  • Validation of a photogrammetric technique for computing equine hoof volume.Labens R, Redding WR, Desai KK, Vom Orde K, Mansmann RA, Blikslager AT. | Vet J. 2013 197:625-30

  • (2015) Operative Factors Associated with Short-term Survival in Horses with Large Colon Volvulus: 47 cases from 2006 to 2013.Gonzalez LM, Fogle CF, Baker WT, Hughes FE, Law JM, Motsinger-Reif AA, Blikslager AT. | Equine Vet J 2015;47(3)279-84. PMID:24735170.

  • (2015) Animal models of ischemia-reperfusion induced intestinal injury: progress and promise for translational research.Gonzalez LM, Moeser AJ, Blikslager AT. | Am J Physiol Gastrointest Liver Physiol 2015;308(2)G63-75. PMID:25414098.

  • (2015) Characterization of Discrete Equine Intestinal Epithelial Cell Lineages.Gonzalez LM, Kinnin LS, Blikslager AT. | Am J Vet Res 2015;76(4)358-66. PMID:25815577

  • (2015) Porcine models of digestive disease: the future of large animal translational research. Gonzalez LM, Moeser AJ, Blikslager AT. | Translational Research 2015;166(1)12-27. PMID:25655839.

  • (2016) The key to translational discovery in digestive disease.Ziegler A, Gonzalez LM, Blikslager AT. |

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