Brian T Helfand
Adjunct Assistant Professor of Cell and Molecular
Department of Cell & Molecular Biology
Northwestern University Feinberg School of Medicine
United States of America
Biography
Dr. Brian Helfand is a research assistant professor in the Department of Urology. He completed his MD/PhD at Northwestern University and is continuing with his clinical education in urology. His research focus is directed towards identifying the cellular and molecular mechanisms underlying prostate cancer. Specifically, he is interested in the changes in both the cytoskeletal and nucleoskeletal intermediate filament proteins which promote metastases and disease progression. In addition, he is focused upon elucidating the mechanisms by which intermediate filaments control the expression of DNA (transcription) and their combined influence on cell behavior.
Research Interest
Urology, Prostate Cancer, Cell Biology, Cytoskeleton, Genetics
Publications
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Reconstruction of urethral erosion in men with a neurogenic bladder. Meeks JJ, Erickson BA, Helfand BT, Gonzalez CM BJU international 2009 Feb; 103(3):378-81 PMID: 18778346
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Ureterovaginal fistula formation after oocyte retrieval. Mongiu AK, Helfand BT, Kielb SJ Urology 2009 Feb; 73(2):444.e1-3 PMID: 18384861
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Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy. Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ, Kozlowski J, Smith N, Kundu SD, Yang G, Raji AA, Javonovic B, Pins M, Lindholm P, Guo Y, Catalona WJ, Lee C Clinical cancer research : an official journal of the American Association for Cancer Research 2009 May 15; 15(10):3557-67 PMID: 19447876
