C David James
Professor of Neurological Surgery and Biochemistry
Department of Biochemistry and Molecular Genetics
Northwestern University Feinberg School of Medicine
United States of America
Biography
PhD: Wright State University School of Medicine, Biomedical Sciences (1986) Postdoctoral Fellowship: McGill University, Canada, Tumor Biology (1989)
Research Interest
My primary research interest and activity involves the use of human brain tumor xenograft models for identifying effective therapeutics to treat brain tumor patients, as based on specific molecular characteristics of each patient’s tumor.
Publications
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Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo Sita TL, Kouri FM, Hurley LA, Merkel TJ, Chalastanis A, May JL, Ghelfi ST, Cole LE, Cayton TC, Barnaby SN, Sprangers AJ, Savalia N, James CD, Lee A, Mirkin CA, Stegh AH Proceedings of the National Academy of Sciences of the United States of America. 2017 Apr 18; 114(16): 4129-4134. doi:http://dx.doi.org/10.1073/pnas.1702736114. PMID: 28373576 PMCID: 28373576 ISSN: 0027-8424
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Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing Hill VK, Kim JS, James CD, Waldman T PLoS ONE. 2017 May; 12(5): doi:http://dx.doi.org/10.1371/journal.pone.0176683. PMID: 28464039 PMCID: 28464039 ISSN: 1932-6203
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Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, Zheng H, James CD, Burant CF, Chandel NS, Davuluri RV, Horbinski C, Stegh AH Cell Reports. 2017 May 30; 19(9): 1858-1873. doi:http://dx.doi.org/10.1016/j.celrep.2017.05.014. PMID: 28564604 ISSN: 2211-1247
