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Molecular Biology Experts

David Kamp

Professor of Medicine (Pulmonary and Critical Care
Department of Cell & Molecular Biology
Northwestern University Feinberg School of Medicine
United States of America

Biography

MD: Wayne State University (1981) Residency: Northwestern University, McGaw Medical Center (1984) Fellowship: Northwestern University, McGaw Medical Center (1987) Board Certification: Internal Medicine, Pulmonary Disease

Research Interest

1. Clinical interests: • interstitial lung disease • copd / asthma • dyspnea • drug-induced lung disease 2. Research interests • Mechanism of alveolar epithelial cell injury: role of iron-derived free radicals, the mitochondria, p53 and DNA damage • Asbestos and airborne particulate matter

Publications

  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis Kim SJ, Cheresh P, Eren M, Jablonski RP, Yeldandi A, Ridge KM, Scott Budinger GR, Kim DH, Wolf M, Vaughan DE, Kamp DW American Journal of Physiology - Lung Cellular and Molecular Physiology. 2017 Jan; 313(1): L16-L26. doi:http://dx.doi.org/10.1152/ajplung.00063.2017. PMID: 28428174 ISSN: 1040-0605

  • Lrp5/b-Catenin signaling controls lung macrophage differentiation and inhibits resolution of fibrosis Sennello JA, Misharin AV, Flozak AS, Berdnikovs S, Cheresh P, Varga J, Kamp DW, Budinger GRS, Gottardi CJ, Lam AP American Journal of Respiratory Cell and Molecular Biology. 2017 Feb; 56(2): 191-201. doi:http://dx.doi.org/10.1165/rcmb.2016-0147OC. PMID: 27668462 PMCID: 27668462 ISSN: 1044-1549

  • SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis Jablonski RP, Kim SJ, Cheresh P, Williams DB, Morales-Nebreda L, Cheng Y, Yeldandi A, Bhorade S, Pardo A, Selman M, Ridge K, Gius D, Budinger GR, Kamp DW FASEB Journal. 2017 Jun; 31(6): 2520-2532. doi:http://dx.doi.org/10.1096/fj.201601077R. PMID: 28258190 PMCID: 28258190 ISSN: 0892-6638

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