Douglas M Freymann
Associate Professor of Biochemistry and Molecular
Department of Biochemistry and Molecular Genetics
Northwestern University Feinberg School of Medicine
United States of America
Biography
We determine the three-dimensional structures of proteins in order to understand the structural basis for and functional mechanisms of interactions between proteins and between proteins and small molecules that play important roles cell biology.
Research Interest
Proteins, Macromolecules, Biophysics,Infectious Diseases-parasite
Publications
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Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge) Freymann DM, Nakamura Y, Focia PJ, Sakai R, Swanson GT Acta Crystallographica Section D: Biological Crystallography. 2012 Sep; 68(9): 1163-1174. doi:http://dx.doi.org/10.1107/S0907444912022834. PMID: 22948917 PMCID: 22948917 ISSN: 0907-4449
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Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro Klosowiak JL, Focia PJ, Chakravarthy S, Landahl EC, Freymann DM, Rice SE EMBO Reports. 2013 Nov; 14(11): 968-974. doi:http://dx.doi.org/10.1038/embor.2013.151. PMID: 24071720 PMCID: 24071720 ISSN: 1469-221X
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Structural insights into Parkin substrate lysine targeting from minimal Miro substrates Klosowiak JL, Park S, Smith KP, French ME, Focia PJ, Freymann DM, Rice SE Scientific Reports. 2016 Sep 8; 6: doi:http://dx.doi.org/10.1038/srep33019. ISSN: 2045-2322
