Katherine Rose Sadleir
Research Assistant Professor of Cell and Molecular
Department of Cell & Molecular Biology
Northwestern University Feinberg School of Medicine
United States of America
Biography
PhD: University of Chicago, Molecular Genetics and Cell Biology (2006)
Research Interest
Cell and Molecular Biology
Publications
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Aß reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level Sadleir KR, Eimer WA, Cole SL, Vassar R Molecular Neurodegeneration. 2015 Jan; 10(1): doi:http://dx.doi.org/10.1186/1750-1326-10-1. PMID: 25567526 PMCID: 25567526 ISSN: 1750-1326
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Aß reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level. Sadleir K, Eimer W, Cole S, Vassar R Molecular Neurodegeneration. 2015 Jan 7; 10(1):
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Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aß generation in Alzheimer’s disease Sadleir KR, Kandalepas PC, Buggia-Prévot V, Nicholson DA, Thinakaran G, Vassar R Acta Neuropathologica. 2016 Mar 18; 1-22. doi:http://dx.doi.org/10.1007/s00401-016-1558-9. PMID: 26993139 PMCID: 26993139 ISSN: 0001-6322