Global

Biochemistry Experts

Rex L Chisholm

Professor of Cell and Molecular Biology and Surger
Department of Cell & Molecular Biology
Northwestern University Feinberg School of Medicine
United States of America

Biography

A primary goal of my work is to establish the approaches and benefits of genomics informed personalized medicine. A key element of this is participation in the eMERGE consortium (http://gwas.net), where I serve as the steering committee chair. This project uses Electronic Health Records linked biobank samples (www.nugene.org) to study the genetics of disease susceptibility, therapeutic outcomes and pharmacogenomics. My group is also interested in genome informatics, particularly genome annota...

Research Interest

Biotechnology, Genomics, Bioinformatics

Publications

  • Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network Bush WS, Crosslin DR, Owusu-Obeng A, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, Kitchner T, Manzi S, Mejia AR, Pan V, Perry CL, Peterson JF, Prows CA, Ralston J, Scott SA, Scrol A, Smith M, Stallings SC, Veldhuizen T, Wolf W, Volpi S, Wiley K, Li R, Manolio T, Bottinger E, Brilliant MH, Carey D, Chisholm RL, Chute CG, Haines JL, Hakonarson H, Harley JB, Holm IA, Kullo IJ, Jarvik GP, Larson EB, McCarty CA, Williams MS, Denny JC, Rasmussen-Torvik LJ, Roden DM, Ritchie MD Clinical Pharmacology and Therapeutics. 2016 Aug; 160-169. doi:http://dx.doi.org/10.1002/cpt.350. PMID: 26857349 PMCID: 26857349 ISSN: 0009-9236

  • Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium Verma SS, Cooke Bailey JN, Lucas A, Bradford Y, Linneman JG, Hauser MA, Pasquale LR, Peissig PL, Brilliant MH, McCarty CA, Haines JL, Wiggs JL, Vrabec TR, Tromp G, Ritchie MD, Bickel J, Chandler A, Holm I, Kohane I, Manzi S, Markianos K, Palmer N, Perry C, Savova G, Wolf W, Wong Kong S, Antommaria A, Cobb B, Harley J, Hutton J, Lingren T, Lynch J, Marsolo K, Myers M, Namjou B, Prows C, Solti I, Vinks S, Wagner M, Abrams D, Almoguera B, Chiavacci R, Connolly J, Devoto M, Hakonarson H, Keating B, Kim C, Mentch F, Qui H, Sleiman P, Tian L, Vazquez L, Bartko B, Bock J, Borthwick K, Carey D, Colonie R, Elston R, Faucett A, Fetterolf S, Gerhard G, Kuivaniemi H, Ledbetter D, Lipsky E, Pendergrass S, Sundaresan A, Smelser D, Williams J, Williams M, Wood C, Albrecht J, Carlson C, Carrell D, Crane P, Cronkite D, Crosslin D, Davis C, Ehrlich K, Fullterton M, Gallego C, Gordon A, Grafton J, Hansen K, Hartzler A, Jarvik G, Larson E, Leppig K, Mukherjee S, Ralston J, Scrol A, Tarczy-Hornoch P, Trinidad S, Bielinski S, Bruce K, Chute C, De Andrade M, Jouni H, Heit J, Isseh I, Koenig B, Kullo I, Li D, McCormick J, Pathak J, Russell J, Schultz C, Vitek C, Wussow L, Sharp R, Olson A, Chandra H, Armstrong G, Berg R, Brautbar A, Brilliant M, Finamore J, Frost N, Hall M, He M, Kitchner T, Lin S, Linneman J, McCarty C, Peissig P, Shefali S, Strenn R, Weichelt B, Bagiella E, Bottinger E, Dieterich D, Ellis S, Ferryman K, Friedman C, Friedman S, Galarneau G, Gomez A, Gottesman O, Hulot JS, Horowitz C, Hripcsak G, Kannry J, Kenny E, Keppel Y, Lin J, Lotay V, Mejia A, Nadukuru R, Peter I, Rhodes R, Sanderson S, Scott S, Ullman T, Weijia Z, Weng C, Zinberg R, Armstrong L, Aufox S, Baker D, Cameron K, Chisholm R, Christensen C, Greenland P, Hayes G, Heathcote M, Kho A, Lowe B, Jackson K, Pacheco J, Pan V, Persell S, Rasmussen L, Rasmussen-Torvik L, Smith M, Starren J, Thompson W, Wicklund C, Brothers K, Chen L, Clayton E, Cowan J, Crawford D, Denny J, Edwards T, Harris P, Garrison N, Malin B, McGregor T, Peterson J, Roden D, Speltz P, Stallings S, Stroud M, Velez D, Van Driest S, Wilke R, Basford M, Claar MB, Hardebeck A, Kirby J, Ritchie M, Setia S, Kaufman D, Li R, Manolio T, Allingham RR, Budenz DL, Kang JH, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Liu Y, Moroi SE, Realini A, Ritch R, Richards JE, Schuman JS, Scott B, Singh K, Vollrath D, Weinreb RN, Wollstein G, Yaspan BL, Yoneyama S, Zack D, Zhang K, Pericak-Vance M, , PLoS Genetics. 2016 Sep; 12(9): doi:http://dx.doi.org/10.1371/journal.pgen.1006186. PMID: 27623284 PMCID: 27623284 ISSN: 1553-7390

  • Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans Nadkarni GN, Galarneau G, Ellis SB, Nadukuru R, Zhang J, Scott SA, Schurmann C, Li R, Rasmussen-Torvik LJ, Kho AN, Hayes MG, Pacheco JA, Manolio TA, Chisholm RL, Roden DM, Denny JC, Kenny EE, Bottinger EP Journal of the American College of Cardiology. 2017 Mar 28; 69(12): 1564-1574. doi:http://dx.doi.org/10.1016/j.jacc.2017.01.040. PMID: 28335839 PMCID: 28335839 ISSN: 0735-1097

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