Rintaro Hashizume
Assistant Professor of Neurological Surgery and Bi
Department of Biochemistry and Molecular Genetics
Northwestern University Feinberg School of Medicine
United States of America
Biography
MD: St. Marianna University (1990) PhD: St. Marianna University, Clinical Pathology (1996) Residency: St. Marianna University, Surgery (1992) Residency: St. Marianna University, Chief Medical Resident (1997) Postdoctoral Fellowship: University of Texas, MD Anderson Cancer Center, Biochemistry (1999)
Research Interest
Dr. Hashizume's primary research interests in understanding of the molecular mechanisms, that affect the aggressive/ invasive biological behavior of pediatric malignant glioma and would accordingly reveal potential therapeutic targets for glioma therapy.
Publications
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Therapeutic Hypothesis Testing With Rodent Brain Tumor Models Wainwright DA, Horbinski CM, Hashizume R, James CD Neurotherapeutics. 2017 Mar 20; 1-8. doi:http://dx.doi.org/10.1007/s13311-017-0523-1. PMID: 28321824 PMCID: 28321824 ISSN: 1933-7213
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A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2 Zhou J, Tien AC, Alberta JA, Ficarro SB, Griveau A, Sun Y, Deshpande JS, Card JD, Morgan-Smith M, Michowski W, Hashizume R, James CD, Ligon KL, Snider WD, Sicinski P, Marto JA, Rowitch DH, Stiles CD Cell Reports. 2017 Mar 28; 18(13): 3167-3177. doi:http://dx.doi.org/10.1016/j.celrep.2017.03.003. PMID: 28355568 PMCID: 28355568 ISSN: 2211-1247
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Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, James CD, Shilatifard A Nature Medicine. 2017 Apr; 23(4): 493-500. doi:http://dx.doi.org/10.1038/nm.4296. PMID: 28263307 ISSN: 1078-8956
