Gaurav Varshney
Assistant Professor
Functional & Chemical Genomics Research
Oklahoma Medical Research Foundation
United States of America
Biography
M.Sc., GB Pant University of Agriculture & Technology, Pantnagar, India, 1999 Ph.D., Umeå University, Umeå, Sweden, 2008 Postdoc, (Mentor: Shawn Burgess) National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 2009-2016
Research Interest
Development of Novel CRISPR-based Strategies for Functional Genomics in Zebrafish; tackling the challenge of systematically validating the flood of human candidate disease genes identified in various genome- wide association (GWAS) and whole-exome sequencing studies with the additional goal of generating animal models for the validated disease genes.
Publications
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Varshney GK, Carrington B, Pei W, Bishop K, Chen Z, Fan C, Xu L, Jones M, LaFave MC, Ledin J, Sood R, Burgess SM. A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Nat Protoc. 2016 Dec;11(12):2357-75. PMID: 27809318
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Watkins-Chow DE*, Varshney GK*, Garrett LJ, Chen Z, Jimenez EA, Rivas C, Bishop KS, Sood R, Harper UL, Pavan WJ, Burgess SM. Highly Efficient Cpf1-Mediated Gene Targeting in Mice Following High Concentration Pronuclear Injection. G3(Bethesda). 2017 Feb 9;7(2):719-722. PMCID:PMC5295614* Joint first authors
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Varshney GK, Kintali SR, Das K. Effect of Curcumin Addition on the Adsorption and Transport of a Cationic Dye across DPPG-POPG Liposomes Probed by Second Harmonic Spectroscopy. Langmuir. 2017 Aug 8. PMID: 28742369