David M. Eckmann
Professor
Department of Anesthesiology and Critical Care MedicineÂ
Pennsylvania State University
United States of America
Biography
Dr. David M. Eckmann is working as Professor of Department of Anesthesiology & Critical Care at The University of Pennsylvania Health System. He is also working as Member, Institute for Medicine and Engineering, University of Pennsylvania Institute for Medicine and Engineering, Founding Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania Institute for, Translational Medicine and Therapeutics, Member, Cardiovascular Institute, University of Pennsylvania Cardiovascular Institute, Professor of Bioengineering, University of Pennsylvania (Secondary Appointment), Adjunct Investigator, University of Pennsylvania Institute for Environmental Medicine, Member, University of Pennsylvania Nano/Bio Interface Center. He received his Ph.D. (Biomedical Engineering) from Northwestern University, 1989. His research interests include: Cellular metabolic engineering. We are examining the relationship between cellular metabolic function and cellular mechanical function. Our goal is to understand mitochondrial function and cellular bioenergetics in the face of cellular mechanical dysfunction and to understand maintenance of cellular mechanical homeostasis when cellular metabolic capacity becomes stressed.
Research Interest
to understand mitochondrial function and cellular bioenergetics in the face of cellular mechanical dysfunction and to understand maintenance of cellular mechanical homeostasis when cellular metabolic capacity becomes stressed.
Publications
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Kandel J, Chou P, Eckmann DM, (2015) Automated detection of whole-cell mitochondrial motility and its dependence on cytoarchitectural integrity. Biotechnology & Bioengineering 112: 1395-1405
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Kandel J, Angelin AA, Wallace DC, Eckmann DM, (2016) Mitochondrial respiration is sensitive to cytoarchitectural breakdown. Integrative Biology 8: 1170-1182
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Grady ME, Parrish E, Seeger S, Caporizzo MA, Composto RJ, et al. (2017) Intracellular nanoparticle dynamics affected by cytoskeletal integrity. Soft Matter 13: 1873-1880