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David P. Cormode

Assistant Professor
Department of Medicine
Pennsylvania State University
United States of America

Biography

Dr. David P. Cormode is affiliated to Department of Medicine, The University of Pennsylvania Health System. Dr. David P. Cormode is currently providing services as Assistant Professor. Dr. David P. Cormode authored and co-authored multiple the development of novel and multifunctional nanoparticle contrast agents for medical imaging applications. A current major area is the development of gold and bismuth nanoparticles as contrast agents for computed tomography (CT). The nanoparticles can be further modified to have a variety of additional functional properties, such as fluorescence, MRI contrast or therapeutic effects. Related areas of interest are novel computed tomography-based imaging methods, such as dual energy CT, spectral CT and iterative image reconstruction. These technologies are being applied for structural imaging and molecular imaging of the levels of specific cell types and proteins in vivo. These approaches provide enhanced characterization of cardiovascular diseases and cancers, which should allow improved selection of therapies and monitoring of response to treatments..

Research Interest

the development of novel and multifunctional nanoparticle contrast agents for medical imaging applications. A current major area is the development of gold and bismuth nanoparticles as contrast agents for computed tomography (CT). The nanoparticles can be further modified to have a variety of additional functional properties, such as fluorescence, MRI contrast or therapeutic effects. Related areas of interest are novel computed tomography-based imaging methods, such as dual energy CT, spectral CT and iterative image reconstruction. These technologies are being applied for structural imaging and molecular imaging of the levels of specific cell types and proteins in vivo. These approaches provide enhanced characterization of cardiovascular diseases and cancers, which should allow improved selection of therapies and monitoring of response to treatments.

Publications

  • Cormode David P, Si-Mohamed Salim, Bar-Ness Daniel, Sigovan Monica, Naha Pratap C, et al. (2017) Multicolor spectral photon-counting computed tomography: in vivo dual contrast imaging with a high count rate scanner Scientific Reports 7: 4784.

  • Chhour Peter, Kim Johoon, Benardo Barbara, Tovar Alfredo, Cormode David P, et al. (2017) Effect of gold nanoparticle size and coating on labeling monocytes for CT tracking Bioconjugate Chemistry 28: 260-269.

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