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Garret Adare Fitzgerald

Professor
Pharmacology
Pennsylvania State University
United States of America

Biography

Dr. Garret Adare FitzGerald is affiliated to Pharmacology, The University of Pennsylvania Health System. Dr. Garret Adare FitzGerald is currently providing services as Professor. Dr. Garret Adare FitzGerald authored and co-authored multiple prostanoid biology and the role of peripheral molecular clocks in cardiovascular biology, metabolism and aging. Perhaps the distinguishing feature of our groups is that we pursue interdisciplinary translational science with a focus on therapeutics. Thus, we work in different model systems – mammalian cells, worms, fish and mice – but also in humans. Ideally we develop quantitative approaches that can be projected from our experiments in the model systems to guide elucidation of drug action in humans. To this end, we have long utilized mass spectrometry, initially to target the arachidonate derived lipidome, but more latterly also the proteome..

Research Interest

prostanoid biology and the role of peripheral molecular clocks in cardiovascular biology, metabolism and aging. Perhaps the distinguishing feature of our groups is that we pursue interdisciplinary translational science with a focus on therapeutics. Thus, we work in different model systems – mammalian cells, worms, fish and mice – but also in humans. Ideally we develop quantitative approaches that can be projected from our experiments in the model systems to guide elucidation of drug action in humans. To this end, we have long utilized mass spectrometry, initially to target the arachidonate derived lipidome, but more latterly also the proteome.

Publications

  • Catella-Lawson F, Reilly MP, Kapoor SC, Cucchiara AJ, FitzGerald GA, et al. (2001) Cyclooxygenase inhibitors and the antiplatelet effects of aspirin New Engl J Med 345: 1809-1817.

  • Grosser T, Yusuff S, Cheskis E, Pack MA, FitzGerald GA (2002) Developmental expression of functional cyclooxygenases in zebrafish Proc Natl Acad Sci (USA) 99: 8418-8423.

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