Molecular Biology
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J. Kevin Foskett

Professor
Cell and Developmental Biology
Pennsylvania State University
United States of America

Biography

Dr. J. Kevin Foskett is affiliated to Cell and Developmental Biology, The University of Pennsylvania Health System. Dr. J. Kevin Foskett is currently providing services as Professor. Dr. J. Kevin Foskett authored and co-authored multiple membrane transport and cell signaling. The techniques we employ in the lab span the spectrum from biophysical to molecular. Biochemical and molecular tools are used within the context of physiological measurement, with the goal to understand how molecular behavior results in complex cell physiological processes in normal and disease states. We employ electrophysiology, including single ion channel patch clamping and two-electrode voltage clamping; digital low light-level fluorescence imaging microscopy of single living cells; micro-injection; yeast 2-hybrid system to examine and discover protein interactions; recombinant protein expression; molecular biology; and biochemistry..

Research Interest

membrane transport and cell signaling. The techniques we employ in the lab span the spectrum from biophysical to molecular. Biochemical and molecular tools are used within the context of physiological measurement, with the goal to understand how molecular behavior results in complex cell physiological processes in normal and disease states. We employ electrophysiology, including single ion channel patch clamping and two-electrode voltage clamping; digital low light-level fluorescence imaging microscopy of single living cells; micro-injection; yeast 2-hybrid system to examine and discover protein interactions; recombinant protein expression; molecular biology; and biochemistry.

Publications

  • Vais H, Mallilankaraman K, Mak DO, Hoff H, Foskett JK, et al. (2016) EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter Cell Rep 14: 403-10.

  • Ma Z, Tanis JE, Taruno A, Foskett JK (2015) Calcium homeostasis modulator (CALHM) ion channels Pflugers Arch.

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