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Alexander Ploss

Assistant professor
Molecular Biology
Princeton University
United States of America

Biography

Alexander Ploss, Ph.D. completed his Bachelor's and Master's degree in biochemistry at the University of Tübingen, Germany including additional training the Howard Hughes Medical Institute at the University of Washington, Seattle, and at the German Cancer Research Center in Heidelberg, Germany. Dr. Ploss completed his Ph.D. in Immunology at Memorial Sloan-Kettering Cancer Center/Cornell University and postdoctoral training at the Rockefeller University. Prior to joining the Department of Molecular Biology at Princeton University in 2013 he was a research associate professor at the Center for the Study of Hepatitis C at the Rockefeller University. His research focuses on immune responses and pathogenesis to human infectious diseases, including hepatitis viruses, related flaviviruses, and malaria. His group combines tissue engineering, molecular virology/pathogenesis, and animal construction, to create and apply innovative technologies including humanized mouse models for the study and intervention of human hepatotropic infections. In recognition of his work he received a Kimberly Lawrence Cancer Research Discovery Fund Award, the Astellas Young Investigator Award of the Infectious Diseases Society of America and the Liver Scholar Award from the American Liver Foundation. Professor Ploss is a member of the Genomic Instability and Tumor Progression Program at the Cancer Institute of NJ.

Research Interest

Microbiology and Virology

Publications

  • Douam F, Albrecht YESoto, Hrebikova G, Sadimin E, Davidson C, Kotenko SV, et al., 2017, Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo, J.Mbio, 8

  • Winer BY, Huang TS, Pludwinski E, Heller B, Wojcik F, Lipkowitz GE, et al., 2017, Long-term hepatitis B infection in a scalable hepatic co-culture system, J.Nat Commun., 8, 125.

  • Douam F, Hrebikova G, Albrecht YESoto, Sellau J, Sharon Y, Ding Q, et al., 2017, Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome, J. Nat Commun., 8, 14781

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