Jacques R. Fresco
Emeritus Professor
Molecular Biology
Princeton University
United States of America
Biography
Jacques R. Fresco is a Emeritus Professor of Molecular Biology at Princeton University.He is inetested in a new approach to gene therapy; Cytogenetic probes for amplified cancer-relevant genes;Physical-Chemical studies of nucleic acids; Mutagenic mechanisms and Molecular mechanisms
Research Interest
Life science and Molecular Biology
Publications
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Amosova, O., Smith, A. and Fresco, J.R, 2011, The consensus sequence for self-catalyzed site-specific G-residue depurination in DNA, J. Biol, Chem. 286, 36316-36321
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Amosova, O., Kumar, V., Deutsch, A. and Fresco, J.R., 2011, Self-catalyzed site-specific depurination of G-residues mediated by cruciform extrusion in closed circular DNA plasmids, J. Biol. Chem, 286 36322–36330
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Alvarez-Dominguez JR, Amosova O, Fresco JR, 2013, Self-catalytic DNA depurination underlies human β-globin gene mutations at codon 6 that cause anemias and thalassemias, J Biol Chem, 288, 11581-9