Jeffry B. Stock
Professor
Molecular Biology
Princeton University
United States of America
Biography
Jeffry B. Stock is a leading expert in signal transduction and global cellular regulation with over 150 original scientific articles in this and related areas. He is best known for his seminal work on membrane receptor function and signal transduction in micro-organisms. As a graduate student at Johns Hopkins in the early 70s he played a key role in elucidating the chemiosmotic relationships and bioenergetics of active transport and membrane receptor function in bacteria. As a postdoctoral fellow at Berkeley and later as a Professor and independent investigator at Princeton, Dr. Stock has made numerous contributions toward understanding the molecular mechanism of sensory-motor regulation in prokaryotes. He was the first to elucidate the so-called two-component phosphorelay biochemistry that underlies sensory-motor regulation in specific, and serves generally to regulate bacterial responses to changing environmental conditions.
Research Interest
Biochemistry, Biophysics and Structural Biology
Publications
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Fernández JR, Webb C, Rouzard K, Voronkov M, Huber KL, Stock JB, et al., 2016, N-Acetylglutaminoyl-S-farnesyl-L-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes, J.Arch Dermatol Res, 309, 103-110
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Fernández JR, Rouzard K, Voronkov M, Huber KL, Webb C, Stock JB, et al., 2016, In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities, J Cosmet Dermatol, 15, 150-7
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Park H-J, Lee K-W, Park ES, Oh S, Yan R, Zhang J, et al., 2016, Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies, J.Ann Clin Transl Neurol, 3, 769-780.