Lynn W. Enquist
Professor
Molecular Biology
Princeton University
United States of America
Biography
Lynn W. Enquist is Henry L. Hillman Professor in Molecular Biology and Professor in the Princeton Neuroscience Institute at Princeton University. He received his BS degree in Bacteriology at South Dakota State University in 1967. He received his Ph.D. in Microbiology from Medical College of Virginia, Virginia Commonwealth University in 1971 with S. Gaylen Bradley studying streptomyces biology. He did postdoctoral training at the Roche Institute of Molecular Biology from 1971 to 1973 studying bacteriophage lambda replication and recombination with Ann Skalka. He served in the US Public Health Service from 1973-1981. He was a senior staff fellow at the National Institutes of Health in the laboratory of Dr. Philip Leder working with Robert Weisberg from 1974-1977 studying bacteriophage lambda site-specific recombination and development of recombinant DNA technology. He held a tenured staff position in the National Cancer Institute from 1977 to 1981 where he continued the development of recombinant DNA technology and also began his work on neurotropic herpes viruses. George VandeWoude was his lab chief. In 1981 he left the National Cancer Institute to be Executive Scientist at Molecular Genetics Incorporated in Minnetonka, Minnesota where he worked on recombinant DNA based viral vaccines. In 1984, he joined DuPont as a Research Leader where he ran a laboratory studying neurotropic viruses. In 1990, he joined DuPont Merck Pharmaceutical Company where he was a Senior Research Fellow working on developing neurotropic viruses as tools for gene therapy and studying the mammalian nervous system. In 1993, he accepted the position of tenured full professor of Molecular Biology at Princeton University. He was chair of the department of Molecular Biology from 2004 to 2013
Research Interest
Neurovirology
Publications
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Rosario W, Singh I, Wautlet A, Patterson C, Flak J, Becker TC, et al., 2016, The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions. Diabetes, 65, 2711-23
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Enquist LW, Leib DA., 2107, Intrinsic and Innate Defenses of Neurons: Détente with the Herpesviruses, J Virol. , 91
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Pomeranz LE, Ekstrand MI, Latcha KN, Smith GA, Enquist LW, Friedman JM, 2107, Gene expression profiling with Cre-conditional pseudorabies virus reveals a subset of midbrain neurons that participate in reward circuitry, J. Neurosci., 37, 4128-4144