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Mark P. Brynildsen

Associate Professor
Chemical and Biological Engineering
Princeton University
United States of America

Biography

Dr. Mark P. Brynildsen received his B.S. in Chemical Engineering from Rutgers University, New Brunswick in 2002 and earned his Ph.D. in Chemical Engineering from the University of California, Los Angeles (UCLA) in 2008, where he worked with Dr. James C. Liao. After working for 2 years as a Howard Hughes Medical Institute (HHMI) post-doctoral associate with James J. Collins within the Department of Biomedical Engineering at Boston University, Mark joined the faculty of the Department of Chemical and Biological Engineering at Princeton University as an Assistant Professor in September of 2010. The overarching goal of his research group is to improve the performance of current antibiotics and identify targets for novel anti-infectives. To accomplish this, the Brynildsen group uses computational and experimental techniques in systems biology and metabolic engineering to develop fundamental understanding of the molecular mechanisms and networks pathogens use to thwart immune antimicrobials and antibiotics. Mark’s research has been published in journals such as Nature, Nature Biotechnology, Nature Communications, PNAS, and Molecular Cell, and he has been the recipient of a Howard B. Wentz, Jr. Junior Faculty Award and an NSF CAREER Award.

Research Interest

Applied and Computational Mathematics Bioengineering

Publications

  • Henry TC and Brynildsen MP, 2016 , Quantifying current events identifies a novel endurance regulator, JTM, 5, 324-6

  • "Henry TC and Brynildsen MP, 2016, Development of Persister-FACSeq: a method to massively parallelize quantification of persister physiology and its heterogeneity, JSR, 6, 25100"

  • Gowers GF, Robinson JL, and Brynildsen MP, 2016, Starved Escherichia coli preserve reducing power under nitric oxide stress, JBBRC,

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