Mohamed S. Donia
Assistant professor
Molecular Biology
Princeton University
United States of America
Biography
Dr. Donia received his B.Sc in Pharmacy from the Faculty of Pharmacy, Suez Canal University, Egypt in 2004. He moved to the US in 2005 to study for his Ph.D. at the Medicinal Chemistry Department, School of Pharmacy, University of Utah. He worked in Dr. Eric Schmidt's laboratory where he studied the chemistry and biology of small molecules produced by bacterial symbionts of marine animals. He used chemical, microbiological, and metagenomic techniques to study the role of small molecules in mediating microbe-host and microbe-microbe interactions in marine invertebrates. In 2010, he joined Dr. Michael Fischbach's laboratory at the Department of Bioengineering and Therapeutic Sciences at the University of California, San Francisco. There, he studied small molecules produced by members of the human microbiome and their role in mediating microbe-host and microbe-microbe interactions in humans. In particular, he focused on antibiotics produced by human pathogens and commensals, and their role in shaping the composition and dynamics of the human vaginal and oral microbiota
Research Interest
Microbiology and Virology
Publications
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Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, et al., 2015, Minimum Information about a Biosynthetic Gene cluster, J.Nat Chem Biol., 11, 625-31
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Cervantes-Barragan L, Chai JN, Tianero MDiarey, DiLuccia B, Ahern PP, Merriman J, et al. 2017, Lactobacillus reuteri induces gut intraepithelial CD4(+)CD8αα(+) T cells, J.Science, 357, 806-810
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Guo C-J, Chang F-Y, Wyche TP, Backus KM, Acker TM, Funabashi M, et al, 2017, Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases, J.Cell., 168, 517-526
