Emir Uzay
Assistant Professor
School of Health Sciences
Purdue University
United States of America
Biography
Dr. Uzay E Emir is currently an Assistant Professor in the School of Health Sciences at Purdue University. Having received his PhD degree from Bogazici University, Turkey, in which he studied BOLD fMRI signal transients with different neuro imaging modalities, he broadened his scientific expertise further by undertaking postdoctoral training in the field of ultra high field (UHF) magnetic resonance spectroscopy (MRS) methods. Following this extensive training period, he worked at the FMRIB Centre, University of Oxford, from 2013-2017 as a Head of Magnetic Resonance Spectroscopy. Dr. Emir’s expertise lies in the development and clinical translation of magnetic resonance spectroscopy (MRS) techniques at clinical (3T) and ultra-high field (UHF>3T) magnetic fields. He have used these systems at both 3T and 7T to quantify various brain metabolites, including neurotransmitters (γ-amino butyric acid, GABA, and glutamate, Glu) in Parkinson’s Disease (PD); antioxidants (glutathione, GSH, and ascorbate, Asc) in aging; and oncometabolites (2 hydroxyglutarate, 2-HG, and lactate, Lac) in patients with glioma.
Research Interest
Studying the neurochemical basis of brain plasticity: Developing methods for profiling psychiatric disorders and psychoactive drug discovery Neurochemical profiling of brain cancer Unraveling the neurochemical mechanism of BOLD-fMRI signal
Publications
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Lunghi C, Emir UE, Morrone MC, Bridge H (2015) Short-term monocular deprivation alters GABA in the adult human visual cortex. Curr Biol 25: 1496-1501
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Emir UE, Larkin SJ, de Pennington N, Voets N, Plaha P, Stacey R, Al-Qahtani K, McCullagh J, Schofield CJ, Clare S, Jezzard P, Cadoux-Hudson T, Ansorge O (2016) Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations. Cancer Res 76: 43-49.
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Emir UE, Burns B, Jezzard P, Thomas A (2017), Metabolite-Cycling Short-Echo Time Magnetic Resonance Spectroscopic Imaging using a Concentric Ring k-space Trajectory NMR Biomed 30: e3714.
