Gregory H. Hockerman
Professor
Medicinal Chemistry and Molecular Pharmacology
Purdue University
United States of America
Biography
Dr. Gregory H. Hockerman is employed as Professor of Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University. His research interests include: Voltage-gated calcium channels are key players in a large array of physiological processes including contraction of cardiac, vascular and skeletal muscle, release of neurotransmitters from nerve terminals, gene expression, and hormone secretion. The long-range goal of our studies is to contribute to the development of drugs that can modulate voltage-gated calcium channels in a tissue and type selective manner to treat cardiovascular disease and type II diabetes. He received his Ph.D. from University of Wisconsin, 1991.
Research Interest
Defining the roles of specific voltage-gate Ca2+ channels in pancreatic beta cell function.
Publications
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Pratt EPS, Salyer AE, Guerra ML, Hockerman GH (2015) Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and EPAC1-dependent ERK1/2 activation in INS-1 cells. Mol. Cell. Endocrinol.
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Brown KM, Roy KK, Hockerman GH, Doerksen RJ, Colby DA (2015) Activation of the γ-aminobutyric acid type B (GABAB) receptor by agonists and positive allosteric modulators. J. Med. Chem 58: 6336-6347.
