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Keith M. Stantz

Associate Professor of Health Sciences
Health Sciences
Purdue University
United States of America

Biography

Dr. Keith Stantz is a Professor of Imaging Sciences and Medical Physics within the School of Health Sciences at Purdue University. Dr. Stantz obtained a B.S. degree from Valparaiso University in ECE and Physics (1988); an M.S. degree in Physics from Michigan State University (East Lansing, MI); and a PhD from Indiana University (Bloomington, IN) in particle physics, where he was part of the MEGA research team investigating rare muon decay at Los Alamos National Laboratory. As a Project and Research Scientist at two small companies and IUSM, he developed CT, optical and thermoacoustic imaging instrumentation and methods. As a faculty at Purdue, his research continues to focus on developing diagnostic imaging in the treatment of cancer, and the training of students in the Medical Physics and the field of Imaging Sciences.

Research Interest

Physiological Imaging using Dynamic Contrast-Enhance Imaging Quantify intra-tumor physiology Influence of tumor angiogenic phenotype in cancer progression Investigate intra-tumor hemodynamic response to anti-angiogenic therapies Development of Thermoacoustic CT Imaging Molecular Imaging using Photoacoustic CT-spectroscopy (PCT-S) Particle Beam Dosimetric Imaging using Radiation-induced Acoustic CT (RACT) Modeling and Tumor Biology Mathematical models to fuse in vivo mulit-parametric measurements of tumor hemodynamics Explore influence of hypoxia on cancer stem cell prevalence Investigate influence of anti-angiogenic and radiation therapy on CSCs and inflammatory processes

Publications

  • Stantz KM, Liu B, Cao M, Reinecke D, Miller K, Kruger R ( 2006) Photoacoustic spectroscopic imaging of intra-tumor heterogeneity and molecular identification, Proc. SPIE BIOS 6086: 36-47.

  • Choi M-R, Bardhan R, Stanton-Maxey KJ, Badve S, Nakashatri H, Stantz KM, Cao N, Halas NJ, Clare SE (2012) Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan Horse. Cancer Nanotechnology 3: 47-54

  • Cao N, Cao M, Chin-Sinex H, Mendonca M, Ko S-C, Stantz KM. (2014.) Monitoring the Effects of Anti-angiogenesis on the Radiation Sensitivity of Pancreatic Cancer Xenografts Using Dynamic Contrast-Enhanced CT. Int J of Radiat Oncol Biol Phys 88: 412-8

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