Blanca L. Barquera
chemistry and chemical biology
Rensselaer Polytechnic Institute
United States of America
Dr. Blanca L. Barquera goal is to understand the mechanisms of the enzymes that enable bacteria to create and utilize these ion gradients and to determine the roles played by both the enzymes and gradients in the physiology of the cells. This will provide fundamental insights into the ways that bacteria affect human health, both when they are beneficial and when they are harmful.
bacterial pathogenes, bioenergetics, mechanistic enzymology
Hess V, Gallegos R, Jones JA, Barquera B, Malamy MH, Müller V.Occurrence of ferredoxin:NAD(+) oxidoreductase activity and its ion specificity in several Gram-positive and Gram-negative bacteria. PeerJ. 2016 Jan 11;4:e1515. doi: 10.7717/peerj.1515. PMID: 26793417
Ito, T., Murai, M., Ninokura, S., Kitazumi, Y., Mezic, K.G., Cress, B.F., Koffas, M.A.G., Morgan, J.E., Barquera, B., Miyoshi, H. 2017.Identification of the binding sites for ubiquinone and inhibitors in the Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae by photoaffinity labeling. J Biol Chem. 292: 7727–7742.