Mattheos Koffas
Constellation Professor
School of Science
Rensselaer Polytechnic Institute
United States of America
Biography
Professor Mattheos Koffas, Ph.D., received his B.S. degree in Chemical Engineering from the National Technical University in Athens, Greece in 1994. He then joined the graduate program of the Department of Chemical Engineering at MIT where he worked on improving amino acid biosynthesis from Corynebacterium glutamicum. After completing his Ph.D. in 2000, he joined DuPont’s Central Research and Development as a research scientist where he worked on engineering the carotenoid biosynthesis of an obligate methanotroph. In August of 2002 he joined the faculty of the Department of Chemical and Biological Engineering at SUNY Buffalo as a tenure-track Assistant Professor and was promoted to Associate Professor with tenure in the summer of 2008. In January of 2011 Prof. Koffas moved to his current position at Rensselaer. He was appointed Dorothy and Fred Chau '71 Career Development Constellation Professor in Biocatalysis and Metabolic Engineering in 2015.
Research Interest
Metabolic Engineering, Industrial Microbiology, Synthetic Biology
Publications
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Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules. Cress BF, Englaender JA, He W, Kasper D, Linhardt RJ, Koffas MA. FEMS Microbiol Rev. 2014 Jul;38(4):660-97. doi: 10.1111/1574-6976.12056. Epub 2014 Jan 27.
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Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Xu P, Li L, Zhang F, Stephanopoulos G, Koffas M. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11299-304. doi: 10.1073/pnas.1406401111. Epub 2014 Jul 21.