Biomedical Sciences

Biomedical Sciences Experts

Robert J. Linhardt

chemistry and chemical biology
Rensselaer Polytechnic Institute
United States of America


Robert J. Linhardt received his Ph.D. degree from the Johns Hopkins University (1979) and was a postdoctoral student with Professor Robert Langer at the Massachusetts Institute of Technology (1979-1982) and served on the faculty of University of Iowa from 1982-2003. He is currently the Ann and John H. Broadbent, Jr.'59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering at Rensselaer Polytechnic Institute, holding joint appointments in the Departments of Chemistry and Chemical Biology, Biology, Chemical and Biological Engineering, and Biomedical Engineering. He is an Adjunct Professor of Orthopedics at the Icahn School of Medicine, Mount Sinai, NY. His honors include the American Chemical Society Horace S. Isbell, Claude S. Hudson and Melville L. Wolfrom Awards, the AACP Volwiler Research Achievement Award, the USP Award for an Innovative Response to a Public Health Challenge, is a fellow of the National Academy of Inventors (NAI), a Fellow of the AAAS, and one of the Scientific American Top 10.

Research Interest

Glycoscience, Biocatalysis, Metabolic Engineering


  • Urinary glycosaminoglycans predict outcomes in septic shock and ARDS, E. P. Schmidt, K. H. Overdier, X. Sun, L. Lin, X. Liu, Y. Yang, L. A. Ammons, T. D. Hiller, M. A. Suflita, Y. Yu, Y. Chen, F. Zhang, C. Cothren Burlew, C. L. Edelstein, I. S. Douglas, R. J. Linhardt, American Journal of Respiratory and Critical Care Medicine, in press, 2016.

  • Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in E. coli, B. Cress, J. Jones, K. Daniel, Q. Leitz, J. Englaender, S. Collins, R. J. Linhardt, M. Koffas, Nucleic Acids Research, in press, 2016.

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