Isaac Hilton
Assistant Professor
Department of Bioengineering
Rice University
United States of America
Biography
Isaac Hilton specializes in engineering the human genome and epigenome. He develops CRISPR/Cas9-based technologies and other synthetic biology tools to mechanistically define and control the relationships between epigenetic modifications, gene expression, and cellular processes.Â
Research Interest
Gene expression,
Publications
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Thakore PI, Black JB, Hilton IB, Gersbach CA (2016) Editing the epigenome: technologies for programmable transcription and epigenetic modulation. Nature Methods.
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Hilton IB, Gersbach CA (2015) Enabling functional genomics with genome engineering. Genome Res.Â
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Hilton IB, D’Ippolito AM, Vockley CM, Thakore PI (2015) Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers. Nature Biotechnol.Â
