Kailash Chadha

Biography

Kailash Chadha is working as an Associate Member in the Department of Molecular and Cellular Biology at Roswell Park Cancer Institute. His research interest include: Interferons have significant antiviral, antiproliferative and immunoregulatory activities. Interferons have been used for the treatment of many viral and non-viral malignancies. However, the response to treatment with interferons has been variable. Some patients respond favorably, while others fail to respond. We have shown that this variable response is partially due to the presence of interferon inhibitory activity in their blood circulation. Our laboratory is involved in the isolation and molecular characterization of this interferon inhibitory factor(s)

Research Interest

Interferons have significant antiviral, antiproliferative and immunoregulatory activities. Interferons have been used for the treatment of many viral and non-viral malignancies. However, the response to treatment with interferons has been variable. Some patients respond favorably, while others fail to respond. We have shown that this variable response is partially due to the presence of interferon inhibitory activity in their blood circulation. Our laboratory is involved in the isolation and molecular characterization of this interferon inhibitory factor(s).