Michael Moser

Biography

Dr. Michael Moser works as Assistant Professor of Oncology in the Department of Pharmacology & Therapeutics at Roswell Park Cancer Institute. Our laboratory uses mouse models to understand the molecular mechanism of prostate cancer initiation and progression in order to rationally design therapeutic approaches for the prevention and treatment of the disease. The ultimate goal of the laboratory is to use preclinical testing of potential therapeutic agents to identify promising compounds for clinical use in the treatment of cancer. I am the Director of the Mouse Tumor Models Resource (MTMR) at MTMR, which facilitates animal models research for RPCI investigators. The need for the MTMR arises from the multitude of mouse models of cancer that have been established and characterized. The appropriate use of mouse models requires an in-depth working knowledge of the strengths and limitation of each model, and MTMR provides this expertise. The MTMR provides a full range of services to support animal research at Roswell Park Cancer Institute including serving as a consolidated resource for maintenance of breeding colonies (transgenic, bigenic and trigenic), collection and archiving of samples from MTMR’s murine models (tumor bank), consultation services, development of breeding strategies for genetically engineered mouse models, and technical support for animal studies.

Research Interest

to understand the molecular mechanism of prostate cancer initiation and progression in order to rationally design therapeutic approaches for the prevention and treatment of the disease