Nitai C. Hait
Assistant Professor
Department of Molecular and Cellular Biology
Roswell Park Cancer Institute
United States of America
Biography
Dr. Nitai C. Hait joined the faculty in 2016 as an Assistant Professor of Oncology in the Division of Breast Surgery, Department of Surgical Oncology, and Department of Molecular and Cellular Biology at Roswell Park Cancer Institute. Dr. Hait trained as a molecular biologist at the Bose Institute in Calcutta, India and earned his doctoral degree in the field of Biochemistry and Molecular Biology at the Jadavpur University in Calcutta, India. Dr. Hait did his postdoctoral trainings at the University of Kentucky College Of Medicine in Lexington, Kentucky and at the Virginia Commonwealth University School of Medicine, and the Massey Cancer Center in Richmond, Virginia, where he became an Assistant Professor at the Department of Biochemistry and Molecular Biology.
Research Interest
Role of sphingolipids in inflammation and cancer progression, Role of nuclear receptors in cancer progression, Cancer epigenetics and novel therapeutics, Mechanism of oncogenic signaling in cancer stem cells, Role of lipid signaling in cancer immunotherapy
Publications
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Liang J, Nagahashi M, Kim EY, Harikumar KB, Hait NC, et al. (2013) Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. Cancer Cell 23: 107-20
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Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, et al. (2010) Sphingosine-1-phosphate: a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465: 1084-8
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Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, et al. (2009) Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate. Science 325: 1254-7
