Eric Johnson
Professor
Molecular Medicine
Scripps Research Institute
United States of America
Biography
Eric Johnson is Professor of Molecular Medicine at Scripps Research Institute. He received The Bernard B. Brodie Award in Drug Metabolism, American Society for Pharmacology and Experimental Therapeutics Ronald W. Estabrook, Scientific Achievement Award, International Society for the Study of Xenobiotics;
Research Interest
Molecular Medicine
Publications
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Hsu, M. H., Baer, B. R., Rettie, A. E. & Johnson, E. F. The crystal structure of cytochrome P450 4B1 (CYP4B1) monooxygenase complexed with octane discloses several structural adaptations for ω-hydroxylation. (2017). Journal of Biological Chemistry, 292(13), 5610-5621. PMCID: PMC5392703.
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Albertolle, M. E., Kim, D., Nagy, L. D., Yun, C. H., Pozzi, A., Savas, U., Johnson, E. F. & Guengerich, F. P. Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition. (2017). Journal of Biological Chemistry, 292(27), 11230-11242. PMCID: PMC5500791.
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Butler, C. R., Ogilvie, K., Martinez-Alsina, L., Barreiro, G., Beck, E. M., Nolan, C. E., Atchison, K., Benvenuti, E., Buzon, L., Doran, S., Gonzales, C., Helal, C. J., et al. Aminomethyl-derived beta secretase (BACE1) inhibitors: engaging Gly230 without an anilide functionality. (2017). Journal of Medicinal Chemistry, 60(1), 386-402.