David Feldman
Professor
Medicine
Stanford University
United States of America
Biography
David Feldman is Emeritus Faculty, Acad Council, Medicine - Endocrinology, Gerontology, & Metabolism, Member, Stanford Cancer Institute, he was Awarded for a Career of Outstanding Contributions to Vitamin D Research, Vitamin D Workshop (October 2009)
Research Interest
1. Investigation of the role of vitamin D as a differentiating and antiproliferative agent with the potential to affect malignancy, specifically to benefit breast and prostate cancer. 2. Studies of the metabolic effects of obesity to cause increased risk and worse prognosis in breast cancer in mouse models and in patients with breast cancer. Study of whether vitamin D can reduce the risk and/or improve the likelihood of a better outcome. 3. Study vitamin D action on cancer in cultured cells, in mouse models of cancer and in trials in patients with breast cancer. 4. Analysis of the endocrinologic and molecular mechanisms regulating vitamin D receptor expression and action thereby modulating target organ responsiveness to the actions of vitamin D and its analogs. 5. Elucidation of the molecular basis of hereditary vitamin D resistant rickets, a genetic disease due to mutations in the vitamin D receptor.
Publications
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Narayanan S, Srinivas S, Feldman D (2016) Androgen-glucocorticoid interactions in the era of novel prostate cancer therapy. Nature reviews. Urology 13: 47-60
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Swami S, Krishnan AV, Williams J, Aggarwal A, Albertelli MA, et al. (2016) Vitamin D mitigates the adverse effects of obesity on breast cancer in mice ENDOCRINE-RELATED CANCER 23: 251-264