Jan Carette
Assistant Professor
Microbiology & Immunology
Stanford University
United States of America
Biography
Jan Carette is working as Assistant professor, Microbiology and Immunology in Stanford University. Member of Bio-X and Child Health Research Institute. Faculty Fellow of Stanford ChEM-H.
Research Interest
Our research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it might also facilitate the development of new therapeutic strategies.
Publications
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Pillay S, Meyer NL, Puschnik AS, Davulcu O, Carette JE (2016) An essential receptor for adeno-associated virus infection. Nature 530: 108-112.
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Staring J, von Castelmur E, Blomen VA, Baggen J, Carette JE, et al. (2017) PLA2G16 represents a switch between entry and clearance of Picornaviridae. Nature 541: 412-416.
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Puschnik AS, Majzoub K, Ooi YS, Carette JE (2017) A CRISPR toolbox to study virus-host interactions. NATURE REVIEWS MICROBIOLOGY 15: 351-364.
