Vinit B. Mahajan
Associate Professor
Ophthalmology
Stanford University
United States of America
Biography
Dr. Mahajan is an Associate Professor and vitreoretinal surgeon and scientist in the Department of Ophthalmology at Stanford University. He directs the NIH-funded Omics Laboratory that uses high-throughput methods in genomics, proteomics, and phenomics to identify molecules involved in vitreoretinal disease. His research team discovered the first gene to cause non syndromic uveitis and is now using protein crystallography to design therapeutic inhibitors for calpain-5. Mahajan and his team performed the first CRISPR gene editing therapy for eye disease in human stem cells. They have also created in vivo models for diabetic retinopathy and uveitis.
Research Interest
Development of personalized medicine for eye diseases through translation of our discoveries in proteomics, genomics, and phenomics in humans, mice and tissue culture models.
Publications
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Schaefer KA, Wu WH, Colgan DF, Tsang SH, Bassuk AG et al (2017) Unexpected mutations after CRISPR-Cas9 editing in vivo. Nat Methods 14: 547-548.
