Bernhard Henrich
Professor
Department of Microbiology
State Research Center for Optics and Material Sciences
United States of America
Biography
1983 PhD degree (Dr. rer. nat.) in Microbiology, University of Kaiserslautern 1983-1994 Postdoctoral fellow and research associate at the Group of Microbiology, University of Kaiserslautern 1995 University lecturing qualification (Habilitation) in Microbiology, University of Kaiserslautern 1994-1997 Deputyship for the chair of Microbiology, University of Kaiserslautern 1997-2002 Research associate and lecturer at the Group of Microbiology, University of Kaiserslautern since 2002 Associate Professor (apl. Prof.), Microbiology, University of Kaiserslautern
Research Interest
Lactic acid bacteria constitute a group of related grampositive, obligately fermentative organisms many of which have industrial or medical importance. Lactococci and lactobacilli are extensively used as starters in the fermentation of milk products, vegetables and meat, whereas pneumococci can cause severe infections in humans and animals such as pneumoniae and miningitis. My research focusses on the identification and deliberate modification of functions which are expected to be essential for industrial applications and/or the virulence of the respective bacteria. Examples of such functions are the extracellular polysaccharides of both lactobacilli and pneumococci, proteolytic enzymes of lactobacilli, and antibiotic resistance determinants of pneumococci. A substantial part of our work consists in developing molecular tools for DNA transfer, targeted mutagenesis and controlled gene expression in selected strains of lactic acid bacteria.
Publications
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Weber B, Klein JR, Henrich B (2000) Expression of the phospho-(-glycosidase ArbZ from Lactobacillus delbrueckii subsp. lactis in Lactobacillus helveticus: Substrate induction and catabolite repression. Microbiology 146:1941-1948.
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Neu T, Henrich B (2003) New thermosensitive delivery vector and its use to enable nisin-controlled gene expression in Lactobacillus gasseri. Appl. Environ. Microbiol 69: 1377-1382.
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Altermann E, Henrich B (2003) Transcript map of the temperate Lactobacillus gasseri bacteriophage phi-adh. Microbiology 149: 2987-2999.