Ed Luk

Biography

Ed Luk joined as Professor of Department of Biochemistry and Cell Biology,The Stony Brook University School of Medicine.

Research Interest

Histone proteins are major constituents of the chromosome. DNA wraps around histones to form repeating structural units called nucleosomes. Nucleosomes can then stack onto each other to fold the genomic DNA into a compact, organized structure within the nucleus. For the transcription machinery to ‘read’ the underlying genetic information, the histones must be reorganized and removed at some points. We study the molecular events that mobilize histones to allow the transcription machinery to engage the DNA and turn a gene on or off.