David Erlij
Professor
Physiology and Pharmacology
Suny Downstate Medical Center
United States of America
Biography
David Erlij is Professor in the department of Physiology and Pharmacology at SUNY Downstate Medical Center, United States of America.
Research Interest
Role of different intracellular membrane pools in the regulation of apical membrane permeability in tight epithelia. The goal of these studies is to determine whether different hormones activate apical membrane permeability through the same mechanism. Our initial studies show that the major regulatory pathways involve insertion of preexisting channels from an intracellular pool or pools. We are now investigating whether or not the channels inserted under the influence of different hormones originate in the same or separate membrane pools. The experiments involve continuous measurements of membrane conductance and capacitance.
Publications
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Florán B, Florán L, Erlij D, Aceves J (2004) Activation of dopamine D4 receptors modulates [3H]GABA release in slices of the rat thalamic reticular nucleus. Neuropharmacol 46: 497-503.
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Querejeta E, Valdiosera R, Erlij D, Aceves J (2001) Intrapallidal D2 dopamine receptors control globus pallidus neuron activity in the rat. Neuroscience Lett 300: 78-82.
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Galvan A, Florán B, Erlij D, Aceves J (2001) Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat. J Neural Transmission 108: 153-166.
