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Henri Tiedge

Distinguished Professor
Physiology and Pharmacology
Suny Downstate Medical Center
United States of America

Biography

Henri Tiedge is Research Professor in the department of Physiology and Pharmacology at SUNY Downstate Medical Center, United States of America.

Research Interest

Regulatory RNAs are important mediators of gene expression in eukaryotic cells. At the center of our research are brain cytoplasmic RNAs (BC RNAs), a subtype of regulatory RNA that controls neuronal gene expression at the level of translation. BC RNAs are targeted to synapses where they regulate the synthesis of local proteins. The mechanism is important for long-term structural and functional modulations of synaptic connections, and thus for the control of neuronal excitability and plasticity.

Publications

  • Muslimov IA, Iacoangeli A, Brosius J, Tiedge H (2006) Spatial codes in dendritic BC1 RNA. J Cell Biol 175: 427-439.

  • Iacoangeli A, Tiedge H (2013) Translational control at the synapse: role of RNA regulators. Trends Biochem Sci 38: 47-55.

  • Iacoangeli A, Dosunmu A, Eom T, Stefanov DG, Tiedge H (2017) Regulatory BC1 RNA in cognitive control. Learn Mem 24: 267-277.

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