John Lewis
Professor
Department of Cell Biology
Suny Downstate Medical Center
United States of America
Biography
John Lewis is currently working as Professor of Cell Biology at SUNY Downstate Medical Center, United States of America.
Research Interest
The principal interest of our laboratory is the mechanism of action of Interferons, naturally occurring antiviral agents. In addition to their potent anti-viral activities,interferons can inhibit cell growth, and for this reason are used in cancer chemotherapy, and also to regulate immune responses in multiple ways.
Publications
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Lewis JA, Huq A, Liu W, Jacob A (1995) Induction of antiviral responses and gene activation by intracellular interferon g. Virology 212: 438-450.
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Lewis JA, Huq A, Najarro P (1996) Inhibition of mitochondrial function by Interferon. J Biol Chem 271: 13184-13190.
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Najarro P, Traktman P, Lewis JA (2001) Vaccinia Virus blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activation. J Virol 75 : 3185-3196.
