Steven E. Fox
Professor
Physiology and Pharmacology
Suny Downstate Medical Center
United States of America
Biography
Steven E. Fox is Professor in the department of Physiology and Pharmacology at SUNY Downstate Medical Center, United States of America.
Research Interest
Synaptic Sources of Hippocampal Theta Rhythm This laboratory uses electrophysiological and pharmacological methods to study the EEG theta rhythm in rats to understand how the associated brain state influences information processing by the hippocampus. Theta rhythm occurs during movement and is paced by cholinergic neurons that project from the medial septal nuclei to the hippocampus. The degeneration of these basal forebrain cholinergic neurons is probably the cause of the memory deficit of Alzheimer's patients.
Publications
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Ludvig N, Chao K, Altura BT, Altura BM, Fox SE (1996) Manipulation of pyramidal cell firing in the hippocampus of freely behaving rats by local application of K+ via microdialysis. Hippocampus 6: 97-108.
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Brazhnik ES, Fox SE (1997) Intracellular recordings from medial septal neurons during hippocampal theta rhythm. Exp Brain Res 114: 44.
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Brazhnik ES, Fox SE (1999) Action potentials and relations to the theta rhythm of septohippocampal neurons in vivo. Exp Brain Res 127: 244-458.