John R. Nobile

Biography

 John is a co-founder of Tangen Biosciences, Inc. and has 29 years of experience, including 12 years designing nucleic acid research instruments, and is the lead inventor on over 40 patents.  John started his career at Pitney-Bowes in 1986. For 7 years, he was the lead engineer and chief architect of 7 highly successful products across 3 product lines. For the following 9 years he was a product development consultant, where he was the lead engineer or consulting engineer on over 20 successful products in a variety of industries, including healthcare products such as endoscopic surgical tools and patient monitoring devices.  He was also a consultant to the molded plastics industry, where he provided technical solutions for the most challenging precision part designs. In 2002 John began consulting for 454 Life Sciences, where he eventually joined and became the key architect of the mechanical, fluidic, and disposable kit systems for the first commercial next generation sequencing system, the GS20, launched in 2005.  John was also the chief architect of the much improved GS FLX sequencing platform launched in 2007, and also the GS Junior.  John left 454/Roche in 2009 to go to work for Ion Torrent (acquired by Life Technologies), where he was lead mechanical engineer responsible for the design and implementation of all physical systems.  John Nobile and Dr. Davidson worked together at Life Technologies to launch PGM (Personal Genome Machine), PROTON (larger scale sequencer), and the One Touch emulsion PCR machine.  John is the inventor on over 40 patents, and is an author on multiple next generation sequencing publications.  John has a BS, Mechanical & Materials Engineering from Univ. Conn. John holds a Bachelor of Science, Mechanical and Materials Engineering, from University of Connecticut.

Research Interest

 BIO TECHNOLOGY